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Cryoglobulin
minimum sample volume required ~ 5ml
Test Code: CRY
Tube type: SST
Special instructions
The laboratory MUST be contacted (x4712) to arrange collection of pre-warmed blood tubes in a warm sand flask from the Pathology Laboratory (level 1, B38), Mon-Fri 9am-12noon (analysis cannot take place outside these times).
Sample requirements
ALL SAMPLES MUST be drawn (using vacuette or butterfly but not syringe) into pre-labelled, pre-warmed blood tubes, kept in warm sand and transported immediately to the Pathology Laboratory (level 1, B38).
For new ?Cryoglobulin requests:
Request Cryoglobulin, Serum Electrophoresis, Immunoglobulins, Rheumatoid Factor, Free light chains and Complement analysis.
Draw:
2 x completely full 5 mL yellow top serum samples, request label attached. Place back into warm sand immediately.
AND
2 x completely full 4 mL EDTA samples (purple topped), handwritten label. Place back into warm sand immediately.
AND
1 x Yellow top SST blood tube. Do NOT place into sand, keep at room temperature.
For patients with known Cryoglobulinaemia:
Request Serum Electrophoresis analysis.
Draw:
1 x completely full 5 mL yellow top Serum sample, request label attached.
Contact Laboratory before requesting
Reference range
n/a
Turnaround Time
10
days
Department: Biochemistry
Clinical Application
The purpose of this test is to identify the presence of cryoproteins, these are proteins which precipitate or form a gel at temperatures below body temperature (37°C) and re-dissolve upon warming.
Please note: this test is not currently accredited by UKAS to the ISO 15189 (2012) Standard.
