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Insulin-Like Growth Factor 1
(a.k.a IGF-1)
minimum sample volume required ~ 5ml
Test Code: IGF
Tube type: SST
Other acceptable tube types
Lithium heparin (pale green)
Special instructions
None
Sent away
to Bristol Royal Infirmary
Reference range
Ranges are both age and sex specific, please refer to report, or contact the Duty Biochemist.
Units
nmol/L
Turnaround Time
7
days
Department: Biochemistry
Clinical Application
IGF-1 is a hormone within the family of growth factors and is mainly produced in the liver. IGF-1 mediates the action of growth hormone in peripheral tissues including the bone, kidney, nerves, muscle, amongst others.
IGF-1 analysis is useful in the diagnosis and treatment of growth hormone excess (acromegaly), or deficiency (investigating short stature in children). It may also be useful as a baseline test for micro- and macroadenomas and in annual monitoring in those with macroadenomas.
IGF-1 analysis is NOT indicated for routine hypopituitary screens, or in microadenomas/non-functioning pituitary adenomas (NFPAs).
Please note change in reference range following method change at BRI 13/11/2023.
Links:
» Acromegaly: An Endocrine Society Clinical Practice Guideline
