TPMT (Thio Purine Methyl Transferase)
(a.k.a Azothioprine sensitivity)
minimum sample volume required ~ 4ml
Test Code: TPM
Tube type: EDTA
Special instructions
An additional EDTA sample must be sent if FBC is also requested.
Reference ranges
Deficient: <10
Low: 20-67
Normal: 68-150
High: >150
Sent away
to Sandwell General Hospital, Birmingham
Units
mU/L
Turnaround Time
21
days
Department: Biochemistry
Clinical Application
Identification of patients with low TPMT enzyme levels, which can lead to a risk of toxicity to thiopurine drugs.
Webpage updated: November 2024