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Steroid Profile
Test Code: SPR
Tube type: Universal Container
Special instructions
Random urine (plain) for qualitative analysis. A timed 24hr urine (plain) collection is only required for calculation of daily secretion rates.
For newborns: a faeces free nappy collection can be used. Samples should be collected after day 3 of life.
Urine must be collected before steroid (e.g hydrocortisone) or electrolyte treatment commences.
If glucocorticoid treatment essential: Dexamethasone is preferred.
Clinical details required.
Sent away
to the Department of Clinical Biochemistry, King's College Hospital, London
Contact Laboratory before requesting
Reference range
The steroid reference laboratory provides age appropriate reference data and an interpretation of results based on relevant clinical information.
Turnaround Time
21
days
Department: Biochemistry
Clinical Application
Identification of inborn errors of steroid metabolism: Premature adrenarche; precocious puberty; Gender ambiguity, Male pseudo-hermaphroditism or salt wasting. Life threatening steroid deficiency needs to be identified rapidly.
1. Disorders of adrenal steroid biosynthesis.
2. DSD,Male pseudo-hermaphroditism.
3. Steroid-producing tumours.
4. Steroid sulphatase deficiency.
5. Congenital adrenal hypoplasia.
6. Premature adrenarche / precocious puberty.
Webpage updated: March 2024.
Links:
» King's College Hospital (Synnovis) Urine Steroid Profile Information Page
» Supra-Regional Assay Service (SAS-centre.org) Steroid Profile
