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Gut Hormones
minimum sample volume required ~ 5ml
Test Code: GUT
Tube type: EDTA
Special instructions
A 6-8 hour fast prior to sample collection is required.
For a full gut hormone profile, 3 x EDTA tubes (at least 5mL of blood) must be received on ice within 15 minutes of collection.
For gastrin measurement, H2 blockers should be stopped for 72 hours and omeprazole for 2 weeks prior to blood collection.
Sent away
to Charing Cross Hospital, London
Contact Laboratory before requesting
Reference range
See individual tests
Linked to
Pancreatic polypeptide, Glucagon, Gastrin, Vasoactive intestinal peptide (VIP), Somatostatin and Chromogranin A
Turnaround Time
28
days
Department: Biochemistry
Clinical Application
Please note: Chromogranin B is no longer available as part of the gut hormone profile.
The gut hormone profile is used to aid in the diagnosis of functioning pancreatic neuroendocrine tumours (fPNETs), which may occur as part of Multiple Endocrine Neoplasia (MEN).
Chromogranin A is a general NET biomarker, and is more frequently elevated than other gut tests, but should only be requested where there is a strong suspicion of a NET.
Webpage updated: February 2026.
