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MPO
(a.k.a Myeloperoxidase)
minimum sample volume required ~ 5ml
Tube type: SST
Special instructions
Time limit for add on = 2 days
Human serum or EDTA, heparin or citrate plasma. When using heparin plasma as sample material the MPO antigen band may occasionally show an unspecific, very weak reaction.
Interfering substances = Haemolytic, lipaemic and icteric sera up to a concentration of 5 mg/ml for haemoglobin, of 20 mg/ml for triglycerides and of 0.4 mg/ml bilirubin showed no effect on the analytical results of the present EUROLINE.
Reference range
<9
Units
U/ml
Linked to
ANCA screen
Turnaround Time
14
days
Department: Immunology
Clinical Application
MPO performed after positive ANCA screen.
Associated with organ-limited small vessel necrotising and crescentic glomerulonephritis. MPO is the major antigen giving rise to the p-ANCA fluorescence pattern.
