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Chromogranin A
(a.k.a CgA)
minimum sample volume required ~ 2ml
Test Code: CHA
Tube type: EDTA
Special instructions
For Chromogranin A alone: time from sample collection to receipt into the laboratory can be extended to 30 minutes, with only 1 x EDTA required.
For a full gut hormone profile, 3 x EDTA tubes (at least 5mL of blood) must be received on ice within 15 minutes of collection.
A 6-8 hour fast is preferred, but only essential for full Gut Hormone profile.
Sent away
to Charing Cross Hospital, London
Contact Laboratory before requesting
Reference range
<60
Units
pmol/L
Linked to
Gut Hormones
Turnaround Time
21
days
Department: Biochemistry
Clinical Application
Chromagranins are secreted by most neuroendocrine tumours and can be used for monitoring and detecting recurrence. They are often measured as part of a Gut Hormone profile.
Increased levels can also be seen in patients with decreased renal function, patients with atrophic gastritis and patients with ongoing treatments with proton-pump inhibitory drugs. PPI should be stopped, if possible, for 2 weeks prior to testing.
Webpage updated: February 2026.
