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Chromogranin B
minimum sample volume required ~ 4ml
Test Code: CHB
Special instructions
For a full Gut Hormone profile: 3 EDTA tubes are required, samples should be transported in ice and samples MUST be received in laboratory within 15 minutes of collection.
An 8 hour fast is preferred, but only essential for full Gut Hormone profile
For Chromogranin A or B alone: time can be extended to reach lab within 30 minutes of collection and only 1 x EDTA required.
Sent away
to Charing Cross Hospital, London
Contact Laboratory before requesting
Reference range
<150 pmol/L
Units
pmol/L
Linked to
Gut Hormones
Turnaround Time
21
days
Department: Biochemistry
Clinical Application
Chromagranins are secreted by most neuroendocrine tumours and can be used for monitoring and detecting recurrence. They are often measured as part of a Gut Hormone profile.
Increased levels can also be seen in patients with decreased renal function, patients with atrophic gastritis and patients with ongoing treatments with proton-pump inhibitory drugs. PPI should be stopped, if possible, for 2 weeks prior to testing.
Webpage updated: March 2024.
