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Insulin-Like Growth Factor 2
(a.k.a IGF-2)
minimum sample volume required ~ 5ml
Test Code: IG2
Other acceptable tube types
Lithium heparin (pale green)
Special instructions
None
Sent away
to Royal Surrey County Hospital, Guildford
Reference range
See report or contact the Duty Biochemist.
Units
nmol/L
Turnaround Time
21
days
Department: Biochemistry
Clinical Application
IGF-2 is a peptide hormone mainly synthesised in the liver in adults, amongst other tissues. It is co-secreted with insulin and is responsible for regulating cell growth, differentiation, proliferation, migration and survival. It is particularly important during fetal development and growth, but may also be raised in a number of different cancers.
Measurement of IGF-2 may be useful in the differentiation of spontaneous hypoglycaemia. It may also be useful in determining a source of hypoglycaemia in non-islet cell tumours in cases of severe hypoglycaemia. This is alongside the measurement of IGF-1, insulin, C-peptide, ketones and growth hormone.
Webpage updated: March 2024.
