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PR3
(a.k.a Proteinase 3)
minimum sample volume required ~ 5ml
Tube type: SST
Special instructions
Time limit for add on = 2 days
Human serum or EDTA, heparin or citrate plasma. When using heparin plasma as sample material the MPO antigen band may occasionally show an unspecific, very weak reaction.
Interfering substances = Haemolytic, lipaemic and icteric sera up to a concentration of 5 mg/ml for haemoglobin, of 20 mg/ml for triglycerides and of 0.4 mg/ml bilirubin showed no effect on the analytical results of the present EUROLINE.
Reference range
<3.5
Units
U/ml
Linked to
ANCA Screen
Turnaround Time
14
days
Department: Immunology
Clinical Application
A marker for granulomatosis with polyangiitis (Wegener's Granulomatosis). PR3 is the major antigen giving rise to the c-ANCA fluorescence pattern.
