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Cystatin C
minimum sample volume required ~ 5ml
Test Code: CYN
Other acceptable tube types
Lithium heparin (green)
Special instructions
None
Reference range
0 – 28 days: 0.8 – 2.3
29 – 364 days: 0.7 – 1.5
1 – 17 years: 0.56 – 1.3
18 – 50 years: 0.56 – 0.98
>50 years: 0.61 – 1.4
Sent away
to Manchester University NHS Foundation Trust
Units
mg/L
Turnaround Time
7
days
Department: Biochemistry
Clinical Application
Cystatin C is an endogenous protein synthesised by all nucleated cells. It is a cysteine protease inhibitor.
Cystatin C is relatively freely filtered by the glomeruli, due to its small size. It is reabsorbed by proximal renal tubular cells.
Cystatin C can be used as an alternate marker for renal glomerular function. Cystatin C levels rise as kidney function and glomerular filtration rate decreases.
Webpage updated: November 2024.
