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Transferrin saturation
(a.k.a TSAT, iron binding capacity, TIBC, iron studies)
minimum sample volume required ~ 5ml
Test Code: TRF
Tube type: SST
Other acceptable tube types
Lithium heparin (pale green)
Special instructions
For investigation of possible iron deficiency anaemia please request FERRITIN (not transferrin saturation).
Transferrin saturation is a calculated test, derived from measurement of iron and transferrin.
Reference ranges
Iron <14y: 3 - 25 µmol/L
Iron 14+y: 11 - 32 µmol/L
Transferrin: 2 - 3.6 g/L
Transferrin saturation threshold for further investigation of haemochromatosis (iron overload): >50% males, >40% females
Units
%
Linked to
Iron
Turnaround Time
2
days
Department: Biochemistry
Clinical Application
Iron and transferrin are assayed in order to calculate transferrin saturation, a parameter used in the diagnosis and monitoring of haemochromatosis
Transferrin saturation is also available for assessment of end stage renal failure patients on haemodialysis who may be candidates for erythropoietin therapy, since this index gives a better measure of iron status than ferritin in this situation.
Webpage updated: December 2024
