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ANCA
(a.k.a Anti neutrophil cytoplasmic antibody)
minimum sample volume required ~ 5ml
Tube type: SST
Special instructions
Time limit for add on = 2days.
Interfering substances = This procedure should be performed with a serum specimen. Addition of azide or other preservatives to the test samples may adversely affect the results. Microbially contaminated, heat-treated, or specimens containing visible particulates should not be used. Grossly hemolyzed or lipemic serum specimens should be avoided.
Urgent requests for ANCA MUST be phoned direct to the immunology department (extension 4737)
Reference range
NEG
Linked to
MPO/PR3
Turnaround Time
7
days
Department: Immunology
Clinical Application
Following a positive ANCA screen, samples will be sent for MPO and PR3.
Can be used in conjunction with other laboratory tests and clinical findings to aid in the assessment of systemic small vessel vasculitides. Two main recognised ANCA patterns, pANCA and cANCA, are detectable using the standard ANCA Immunofluorescence procedure on ethanol-fixed neutrophils.
